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luxS [2017-8-11 16:0:3]
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luxS [2017-8-11 16:0:3]

S-ribosylhomocysteine lyase, autoinducer-2 production protein, required for surface spreading motility (sliding) of B. subtilis natto and biofilm formation
Locus
BSU30670
Isoelectric point
5.17
Molecular weight
17.57 kDa
Protein length
157 aa Sequence Blast
Gene length
471 bp Sequence Blast
Function
methionine salvage
Product
S-ribosylhomocysteine lyase
Essential
no
E.C.
4.4.1.21
Synonyms
ytjB

Genomic Context

      
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Categories containing this gene/protein

Gene

Coordinates
3,137,495 → 3,137,968

The protein

Catalyzed reaction/ biological activity

  • S-(5-deoxy-D-ribos-5-yl)-L-homocysteine = L-homocysteine + (4S)-4,5-dihydroxypentan-2,3-dione (according to Swiss-Prot)
  • Protein family

  • luxS family (according to Swiss-Prot)
  • Effectors of protein activity

  • subject to feedback inhibition PubMed
  • Structure

  • 1JQW (complex with homocysteine), 1J98 PubMed
  • Expression and Regulation

    Operons

    Genes
    Description

    Additional information

  • subject to feedback inhibition PubMed
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    Genes
    Description

    Sigma factors

  • SigB: sigma factor, PubMed, in SigB regulon
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    Biological materials

    Mutant

  • MGNA-B540 (ytjB::erm), available at the NBRP B. subtilis, Japan
  • 1A953 ( luxS::cat), PubMed, available at BGSC
  • References

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